Research Highlights: Highlights from the latest articles in colorectal cancer pharmacogenomics

Derek J Jonker, Nirit Yarom, The role of the epidermal growth factor receptor in the mechanism and treatment of colorectal cancer. Discovery Medicine. ,vol. 11, pp. 95- 105 ,(2011)

Howard L McLeod, Sharon Marsh, Pharmacogenetics goes 3D. Nature Genetics. ,vol. 37, pp. 794- 795 ,(2005) , 10.1038/NG0805-794

Sharon Marsh, Pharmacogenetics of colorectal cancer. Expert Opinion on Pharmacotherapy. ,vol. 6, pp. 2607- 2616 ,(2005) , 10.1517/14656566.6.15.2607

Anthony Gonçalves, Séverine Esteyries, Brynn Taylor-Smedra, Arnaud Lagarde, Mounay Ayadi, Geneviève Monges, François Bertucci, Benjamin Esterni, Jean-Robert Delpero, Olivier Turrini, Bernard Lelong, Patrice Viens, Jean-Paul Borg, Daniel Birnbaum, Sylviane Olschwang, Frédéric Viret, A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer. ,vol. 8, pp. 169- 169 ,(2008) , 10.1186/1471-2407-8-169

Guido Bocci, Fotios Loupakis, Bevacizumab pharmacogenetics in tumor treatment: still looking for the right pieces of the puzzle Pharmacogenomics. ,vol. 12, pp. 1077- 1080 ,(2011) , 10.2217/PGS.11.75

Abdelmajid Khabir, Nadir R. Farid, Ahmed Rebaï, Imen Kallel, Maha Rebai, Genetic polymorphisms in the EGFR (R521K) and estrogen receptor (T594T) genes, EGFR and ErbB-2 protein expression, and breast cancer risk in Tunisia. BioMed Research International. ,vol. 2009, pp. 753683- 753683 ,(2009) , 10.1155/2009/753683

Georgios V. Koukourakis, Anastasia Sotiropoulou-Lontou, Targeted therapy with bevacizumab (Avastin) for metastatic colorectal cancer. Clinical & Translational Oncology. ,vol. 13, pp. 710- 714 ,(2011) , 10.1007/S12094-011-0720-Z

Yao-Yu Hsieh, Cheng-Hwai Tzeng, Ming-Huang Chen, Po-Min Chen, Wei-Shu Wang, Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild‐type colorectal cancer patients treated with cetuximab‐based chemotherapy Cancer Science. ,vol. 103, pp. 791- 796 ,(2012) , 10.1111/J.1349-7006.2012.02225.X

R. Engen, S. Marsh, D. Van Booven, H. McLeod, Ethnic Differences in Pharmacogenetically Relevant Genes Current Drug Targets. ,vol. 7, pp. 1641- 1648 ,(2006) , 10.2174/138945006779025446

Zhongyun Zhao, Elise Pelletier, Beth Barber, Monali Bhosle, Song Wang, Sue Gao, David Klingman, Patterns of treatment with chemotherapy and monoclonal antibodies for metastatic colorectal cancer in Western Europe. Current Medical Research and Opinion. ,vol. 28, pp. 221- 229 ,(2012) , 10.1185/03007995.2011.650503