Relationship between cellular DNA synthesis, PCNA expression and sex steroid hormone receptor status in the developing mouse ovary, uterus and oviduct.
作者： S. Li
DOI: 10.1007/BF00268912
关键词:
摘要: The proliferative activities of the different cellular compartments developing mouse ovary, uterus, and oviduct were studied by radioautographic assessment DNA synthesis with [3H]-thymidine labeling immunohistochemical staining proliferating cell nuclear antigen (PCNA). distributions estrogen progesterone receptors (ER PR) staining. values PCNA positive indices a little higher than that indices. However, linear relations shown for two high from postnatal day 1–7 decreased 14 in ovary. on days 1, 3 7 uterus oviduct. Staining ER PR was very weak surface epithelium, stroma large follicles Positive occurred uterine epithelium oviductal epithelium. observed 1 both positivity stromal cells These results suggest appearance steroid differ between compartment reproductive organs. have an inverse relation expression hormone female organs during developmental stages. Therefore, we propose there is autonomous proliferation mechanism development or moderated factors other hormones.
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sci-hub.se 参考文章(39)
Gaëlle Lenglet, Robert Kiss, Jean Lambert Pasteels, André Danguy, Hormonal regulation of uterine epithelial cell proliferation. I. Effects of estradiol or progesterone administered separately. in Vivo. ,vol. 1, pp. 281- 289 ,(1987)
Shinobu Sakamoto, Akio Abe, Hideki Kudo, Noriko Yamada, Keiko Seki, Ryohei Okamoto, Effects of estrogen and progesterone on thymidine kinase activity in the immature rat uterus American Journal of Obstetrics and Gynecology. ,vol. 145, pp. 711- 715 ,(1983) , 10.1016/0002-9378(83)90578-1
Gaëlle Lenglet, Robert Kiss, Jean Lambert Pasteels, André Danguy, Hormonal regulation of uterine epithelial cell proliferation. II. Effects of estradiol and progesterone administered in combination. in Vivo. ,vol. 1, pp. 291- 296 ,(1987)
D.P. Lane, N.H. Waseem, Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form. Journal of Cell Science. ,vol. 96, pp. 121- 129 ,(1990) , 10.1242/JCS.96.1.121
R. M. DAS, L. MARTIN, Progesterone inhibition of mouse uterine epithelial proliferation. Journal of Endocrinology. ,vol. 59, pp. 205- 206 ,(1973) , 10.1677/JOE.0.0590205
TAMARA L. GRECO, J. DAVID FURLOW, THERESA M. DUELLO, JACK GORSKI, Immunodetection of Estrogen Receptors in Fetal and Neonatal Female Mouse Reproductive Tracts Endocrinology. ,vol. 129, pp. 1326- 1332 ,(1992) , 10.1210/ENDO-129-3-1326
Y. TOMOOKA, R. P. DIAUGUSTINE, J. A. McLACHLAN, Proliferation of Mouse Uterine Epithelial Cells in Vitro Endocrinology. ,vol. 118, pp. 1011- 1018 ,(1986) , 10.1210/ENDO-118-3-1011
SHUJI YAMASHITA, RETHA R. NEWBOLD, JOHN A. McLACHLAN, KENNETH S. KORACH, The Role of the Estrogen Receptor in Uterine Epithelial Proliferation and Cytodifferentiation in Neonatal Mice Endocrinology. ,vol. 127, pp. 2456- 2463 ,(1990) , 10.1210/ENDO-127-5-2456
Toshiko Iwai, Yoshihiko Nanbu, Masazumi Iwai, Shunzou Taii, Shingo Fujii, Takahide Mori, Immunohistochemical localization of oestrogen receptors and progesterone receptors in the human ovary throughout the menstrual cycle. Virchows Archiv. ,vol. 417, pp. 369- 375 ,(1990) , 10.1007/BF01606025
Philip W. Hinds, Sibylle Mittnacht, Vjekoslav Dulic, Andrew Arnold, Steven I. Reed, Robert A. Weinberg, Regulation of retinoblastoma protein functions by ectopic expression of human cyclins Cell. ,vol. 70, pp. 993- 1006 ,(1992) , 10.1016/0092-8674(92)90249-C