Utero-ovarian relationships in placental mammals: role of uterus and embryo in the regulation of progesterone secretion by the corpus luteum. A review.

摘要: The role of the uterus and that embryo in regulating luteal progesterone secretion appear to differ greatly, depending on mammal. However, situation is analogous some mammals. main permit establishment maintenance pregnancy, there appears be a relationship between type placenta uterine embryonic modes activity. When placentation endotheliochorial (carnivores), corpus luteum active over remarkably long period; does not have any limiting action species studied presence an profoundly modify secretion. epitheliochorial (artiodactyls), hysterectomy, like uterus, considerably prolongs activity all studied. limits duration by producing luteolytic PGF2 alpha. maintains acting directly causing change synthesis prostaglandins; this eventually favors luteotropic PGE's. Moreover, secretes LH-like possibly prolactin-like factors. hemochorial (rodents, lagomorphs, higher primates), plays slight or none at often increases acts two ways: (a) decidual tissue form endometrium; factors, "prolactin" sometimes PGE, (b) secreting chorionic hormone produced large quantities primates.