Inhibition of tumor necrosis factor-alpha by thalidomide in magnesium deficiency
作者： William B. Weglicki , Richard E. Stafford , Benjamin F. Dickens , I. Tong Mak , Marie M. Cassidy
DOI: 10.1007/BF00926368
关键词:
摘要: The effect of thalidomide on circulating cytokines and myocardial lesion formation was investigated in Mg-deficient rats. After two weeks a diet, rats show an increase levels tumor necrosis factor-alpha interleukin 1. Thalidomide (1 mg/day) caused complete inhibition the levels, without having However, marked cardiomyopathic observed animals treated with thalidomide; possible mechanisms for thalidomide's enhancement injury are discussed. (Mol Cell Biochem129: 195–200, 1993)
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