Relationship between hyperbilirubinaemia and UDP-glucuronosyltransferase 1A1 (UGT1A1) polymorphism in adult HIV-infected Thai patients treated with indinavir
作者： Mark A. Boyd , Preeyaporn Srasuebkul , Kiat Ruxrungtham , Peter I. Mackenzie , Verawan Uchaipichat
DOI: 10.1097/01.FPC.0000197465.14340.D4
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摘要: ObjectivesTo investigate the association between UGT1A1*6 (G71R) and UGT1A1*28 (promoter (TA)7-repeat) genotypes hyperbilirubinaemia in Thai patients treated with indinavir, characterize inhibition of human UGTs by indinavir vitro.MethodsNinety-six HIV receiving indi
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