Cross beta structure comprising amyloid binding proteins and methods for detection of the cross beta structure, for modulating cross beta structures fibril formation and for modulating cross beta structure-mediated toxicity
作者： Barend Bouma , Onno Wouter Kranenburg , Martijn Frans Ben Gerard Gebbink , Louise Maria Johanna Kroon
DOI:
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摘要: The invention relates to the field of biochemistry, molecular biology, structural biology and medicine. More in particular, cross-β structures biological role these structures. In one embodiment, discloses a method for modulating extracellular protein degradation and/or clearance comprising cross-β(beta) structure formation (and/or structure-mediated activity) present circulation.
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