Diagnosis of pseudoprogression using MRI perfusion in patients with glioblastoma multiforme may predict improved survival
作者： Seymur Gahramanov , Csanad Varallyay , Rose Marie Tyson , Cynthia Lacy , Rongwei Fu
DOI: 10.2217/CNS.14.42
关键词:
摘要: SUMMARY Aims: This retrospective study determined the survival of glioblastoma patients with or without pseudoprogression. Methods: A total 68 were included. Overall was compared between showing pseudoprogression (in most cases diagnosed using perfusion MRI ferumoxytol) and in pseudoprogession. MGMT methylation status also analyzed cases. Results: Median 24 (35.3%) 34.7 months (95% CI: 20.3–54.1), 13.4 11.1–19.5) 44 (64.7%) (p < 0.0001). The longest a median 54.1 combination (MGMT) promoter methylation. Conclusion: Pseudoprogression is associated better outcome, especially if concurring Patients never had poor survival. emphasizes importance differentiating tumor progres...
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