Genomic medicine, gene polymorphisms, and human biological diversity.
作者： Bertrand L. Jaber , Vaidyanathapuram S. Balakrishnan , Vaidyanathapuram S. Balakrishnan , Madhumathi Rao , Bertrand L. Jaber
DOI: 10.1111/J.1525-139X.2005.18102.X
关键词:
摘要: There is considerable variation in the prevalence of comorbid conditions such as malnutrition, inflammation, cardiovascular disease, and bone disease among end-stage renal (ESRD) patients on maintenance hemodialysis. Besides traditional risk factors, these differences also arise from variability genetic factors gene-environment interactions. Recent publication human genome sequence through Human Genome Celera projects has provided a major impetus to field molecular genetics genomic medicine. This review provides broad overview recent developments this field, basic information terminology common use, explores impact variations or polymorphisms biological diversity.
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