Chromosome aberrations in 450 sperm complements from eight controls and lack of increase after chemotherapy in two patients.
作者： J. Jenderny , M.L. Jacobi , A. R�ger , G. R�hrborn
DOI: 10.1007/BF00210762
关键词:
摘要: Four hundred fifty sperm complements from eight controls were analyzed. A conservative estimate of aneuploidy was 1.8% with a hyperhaploid rate 0.9% (4/450). The overall frequency structural aberrations 8.9% (40/450). proportion X-bearing (47.5%) and Y-bearing (52.5%) did not differ significantly. Sperm analyzed cancer patient 9 months after polychemotherapy (n = 63) being treated Imurek (azathioprine) 30). There no significant increase in the incidence numerical chromosome either patient. percentages significantly different expected 50%.
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