Prognostic influence of the co-expression of epidermal growth factor receptor and c-erbB-2 protein in human lung adenocarcinoma
作者： M. Tateishi , T. Ishida , S. Kohdono , M. Hamatake , Y. Fukuyama
DOI: 10.1016/0960-7404(94)90006-X
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摘要: Abstract The epidermal growth factor receptor (EGFR) is structurally similar to the c-erbB-2 oncogene protein. One hundred and nineteen specimens of primary human lung adenocarcinoma were investigated immunohistochemically for expression EGFR Positive staining was evident in 55 (46%), protein 33 (28%) cases. Of 119 cases, number positively both totalled 16 (13%). incidence greater patients with metastasis1 (M1) than those MO (P
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