Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
作者： Špela Konjar , Vivien R. Sutton , Sabine Hoves , Urška Repnik , Hideo Yagita
DOI: 10.1111/J.1365-2567.2010.03299.X
关键词:
摘要: … Mouse perforin is a potential substrate for CatL … can cleave perforin, we exposed recombinant, purified mouse perforin to purified CatL in vitro. The recombinant perforin was engineered …
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