Epithelial-mesenchymal transition and its implications for fibrosis.
作者： Eric G. Neilson , Raghu Kalluri
DOI: 10.1172/JCI20530
关键词:
摘要: Epithelial to mesenchymal transition (EMT) is a central mechanism for diversifying the cells found in complex tissues. This dynamic process helps organize the formation of the body …
dm5migu4zj3pb.cloudfront.net 参考文章(153)
Neil A. Bhowmick, Roy Zent, Mayshan Ghiassi, Maureen McDonnell, Harold L. Moses, Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial Plasticity Journal of Biological Chemistry. ,vol. 276, pp. 46707- 46713 ,(2001) , 10.1074/JBC.M106176200
Anthony Person, Raymond B. Runyan, Adriana C. Gittenberger-de Groot, John A. McDonald, Scott E. Klewer, Todd D. Camenisch, Daniël G.M. Molin, Temporal and distinct TGFβ ligand requirements during mouse and avian endocardial cushion morphogenesis Developmental Biology. ,vol. 248, pp. 170- 181 ,(2002) , 10.1006/DBIO.2002.0731
Diane S. Krause, Neil D. Theise, Michael I. Collector, Octavian Henegariu, Sonya Hwang, Rebekah Gardner, Sara Neutzel, Saul J. Sharkis, Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell Cell. ,vol. 105, pp. 369- 377 ,(2001) , 10.1016/S0092-8674(01)00328-2
S Mizuno, T Kurosawa, K Matsumoto, Y Mizuno-Horikawa, M Okamoto, T Nakamura, Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease. Journal of Clinical Investigation. ,vol. 101, pp. 1827- 1834 ,(1998) , 10.1172/JCI1709
S Vidal, E Horvath, K Kovacs, R V Lloyd, H S Smyth, Reversible Transdifferentiation: Interconversion of Somatotrophs and Lactotrophs in Pituitary Hyperplasia Modern Pathology. ,vol. 14, pp. 20- 28 ,(2001) , 10.1038/MODPATHOL.3880252
Q. Al-Awqati, S. Vijayakumar, J. Takito, Terminal differentiation of epithelia. Biological Chemistry. ,vol. 384, pp. 1255- 1258 ,(2003) , 10.1515/BC.2003.138
Brigitte Boyer, Ana Maria Vallés, Natacha Edme, Induction and regulation of epithelial–mesenchymal transitions Biochemical Pharmacology. ,vol. 60, pp. 1091- 1099 ,(2000) , 10.1016/S0006-2952(00)00427-5
Kwonseop Kim, Zifan Lu, Elizabeth D Hay, DIRECT EVIDENCE FOR A ROLE OF β-CATENIN/LEF-1 SIGNALING PATHWAY IN INDUCTION OF EMT Cell Biology International. ,vol. 26, pp. 463- 476 ,(2002) , 10.1006/CBIR.2002.0901
David M. Garrett, Gary W. Conrad, Fibroblast-like cells from embryonic chick cornea, heart, and skin are antigenically distinct. Developmental Biology. ,vol. 70, pp. 50- 70 ,(1979) , 10.1016/0012-1606(79)90006-X
A Desmoulière, Factors influencing myofibroblast differentiation during wound healing and fibrosis. Cell Biology International. ,vol. 19, pp. 471- 476 ,(1995) , 10.1006/CBIR.1995.1090