Development of an in vitro digestive model for studying the peptide profile of breast milk.
作者： Chiara Dall’Asta , Paola Florio , Anna Maria Lammardo , Barbara Prandi , Teresa Mazzeo
DOI: 10.3109/09637486.2015.1042846
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摘要: AbstractHuman milk is a highly valuable food for newborns and infants. Its protein fraction plays an important role the development of newborn. In present study, in vitro digestive model, developed resembling closely system infant, was applied to human order identify characterize peptide profile. The profile obtained after digestion analyzed by μLC-LTQ-Orbitrap-MS. A total 149 peptides from β-casein, 30 α-lactalbumin, 26 αs1-casein, 24 κ-casein, 28 osteopontin, 29 lactoferrin recovered. identified partially hydrolyzed proteins, such as caseins, different that previously reported demonstrating performance neonatal with respect other applied. These results would be useful starting point investigate physiological function breast mil...
sci-hub.se 参考文章(22)
Stanford Moore, On the determination of cystine as cysteic acid. Journal of Biological Chemistry. ,vol. 238, pp. 235- 237 ,(1963) , 10.1016/S0021-9258(19)83985-6
Theresa R. Henderson, Margit Hamosh, Martine Armand, Nitin R. Mehta, Paul Hamosh, Gastric Proteolysis in Preterm Infants Fed Mother’s Milk or Formula Advances in Experimental Medicine and Biology. ,vol. 501, pp. 403- 408 ,(2001) , 10.1007/978-1-4615-1371-1_50
C.B. Furlund, E.K. Ulleberg, T.G. Devold, R. Flengsrud, M. Jacobsen, C. Sekse, H. Holm, G.E. Vegarud, Identification of lactoferrin peptides generated by digestion with human gastrointestinal enzymes Journal of Dairy Science. ,vol. 96, pp. 75- 88 ,(2013) , 10.3168/JDS.2012-5946
Bo Lönnerdal, Bioactive Proteins in Human Milk: Mechanisms of Action The Journal of Pediatrics. ,vol. 156, pp. S26- S30 ,(2010) , 10.1016/J.JPEDS.2009.11.017
Esther Miquel, José Ángel Gómez, Amparo Alegría, Reyes Barberá, Rosaura Farré, Isidra Recio, Identification of casein phosphopeptides released after simulated digestion of milk-based infant formulas. Journal of Agricultural and Food Chemistry. ,vol. 53, pp. 3426- 3433 ,(2005) , 10.1021/JF0482111
Carolien H.M. Versantvoort, Agnes G. Oomen, Erwin Van de Kamp, Cathy J.M. Rompelberg, Adriënne J.A.M. Sips, Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food. Food and Chemical Toxicology. ,vol. 43, pp. 31- 40 ,(2005) , 10.1016/J.FCT.2004.08.007
Vassilios Raikos, Theodore Dassios, Health-promoting properties of bioactive peptides derived from milk proteins in infant food: a review. Dairy Science & Technology. ,vol. 94, pp. 91- 101 ,(2014) , 10.1007/S13594-013-0152-3
Douwina Bosscher, Micheline Van Caillie-Bertrand, Harry Robberecht, Kristien Van Dyck, Rudy Van Cauwenbergh, Hendrik Deelstra, In vitro availability of calcium, iron, and zinc from first-age infant formulae and human milk. Journal of Pediatric Gastroenterology and Nutrition. ,vol. 32, pp. 54- 58 ,(2001) , 10.1097/00005176-200101000-00016
D.E.W Chatterton, J.T Rasmussen, C.W Heegaard, E.S Sørensen, T.E Petersen, In vitro digestion of novel milk protein ingredients for use in infant formulas: Research on biological functions Trends in Food Science and Technology. ,vol. 15, pp. 373- 383 ,(2004) , 10.1016/J.TIFS.2003.12.004
Hans Meisel, Overview on Milk Protein-derived Peptides International Dairy Journal. ,vol. 8, pp. 363- 373 ,(1998) , 10.1016/S0958-6946(98)00059-4