Inflammation on Prostate Needle Biopsy is Associated with Lower Prostate Cancer Risk: A Meta-Analysis

作者: Shaleen R. Vasavada , Ryan W. Dobbs , André A. Kajdacsy-Balla , Michael R. Abern , Daniel M. Moreira

DOI: 10.1016/J.JURO.2017.11.120

关键词:

摘要: Purpose: We performed a comprehensive literature review and meta-analysis to evaluate the association of inflammation on prostate needle biopsies cancer risk.Materials Methods: searched Embase®, PubMed® Web Science™ from January 1, 1990 October 2016 for abstracts containing key words cancer, biopsy. Study inclusion criteria were original research, adult human subjects, cohort or case-control study design, histological biopsy histology. Two independent teams reviewed extracted data selected manuscripts. Combined ORs 95% CIs any, acute chronic calculated using random effects method.Results: Of 1,030 retrieved 46 underwent full text 25 included in final analysis, comprising total 20,585 subjects 6,641 patients with cancer. There was significant heterogeneity among studies (I2 = 84.4%, p...

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