Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment

作者: Catherine Roche-Lestienne , Valerie Soenen-Cornu , Nathalie Grardel-Duflos , Jean-Luc Laı̈ , Nathalie Philippe

DOI: 10.1182/BLOOD.V100.3.1014

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摘要: … In conclusion, our study shows that among different mechanisms of resistance to STI571, … of STI571 may be more prevalent. Our report seems to confirm that Thr315Ile substitution could …

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