Evaluation of microvascular endothelial function in patients with type 1 diabetes using laser-Doppler perfusion monitoring: which method to choose?
作者： Marilia B. Gomes , Alessandra S.M. Matheus , Eduardo Tibiriçá
DOI: 10.1016/J.MVR.2008.04.003
关键词:
摘要: The evaluation of microvascular function is essential in the investigation pathophysiology cardiometabolic diseases [Struijker-Boudier, H.A. et al., 2007. Evaluation microcirculation hypertension and cardiovascular disease. Eur. Heart J. 28, 2834-2840]. In clinical research practice, study great value assessment effects medical interventions monitoring disease progression. It well-known that patients with type 1 2 diabetes have dysfunction results from numerous factors including hyperglycemia, oxidative stress insulin resistance [Schalkwijk, C.G., Stehouwer, C.D., 2005. Vascular complications mellitus: role endothelial dysfunction. Clin. Sci. (Lond). 109, 143-159]. Moreover, skin precedes symptoms end-organ [Khan, F. 2000. Impaired children, adolescents, young adults diabetes. Diabetes Care 23, 215-220]. this study, we assessed using laser-Doppler perfusion (LDPM) coupled physiological pharmacological local vasodilator stimuli.
elsevier.com
sci-hub.se 参考文章(18)
Jimmy Hansell, Loghman Henareh, Stefan Agewall, Mikael Norman, Non-invasive assessment of endothelial function - relation between vasodilatory responses in skin microcirculation and brachial artery. Clinical Physiology and Functional Imaging. ,vol. 24, pp. 317- 322 ,(2004) , 10.1111/J.1475-097X.2004.00575.X
F. Khan, T. A. Elhadd, S. A. Greene, J. J. Belch, Impaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes. Diabetes Care. ,vol. 23, pp. 215- 220 ,(2000) , 10.2337/DIACARE.23.2.215
A.C. Shore, K.J. Price, D.D. Sandeman, E.M. Green, J.H. Tripp, J.E. Tooke, Impaired Microvascular Hyperaemic Response in Children with Diabetes Mellitus Diabetic Medicine. ,vol. 8, pp. 619- 623 ,(1991) , 10.1111/J.1464-5491.1991.TB01667.X
I. T. Meredith, K. E. Currie, T. J. Anderson, M. A. Roddy, P. Ganz, M. A. Creager, Postischemic vasodilation in human forearm is dependent on endothelium-derived nitric oxide American Journal of Physiology-heart and Circulatory Physiology. ,vol. 270, ,(1996) , 10.1152/AJPHEART.1996.270.4.H1435
Stephen J. Leslie, Jonathan Affolter, Martin A. Denvir, David J. Webb, Validation of laser Doppler flowmetry coupled with intra-dermal injection for investigating effects of vasoactive agents on the skin microcirculation in man. European Journal of Clinical Pharmacology. ,vol. 59, pp. 99- 102 ,(2003) , 10.1007/S00228-003-0577-3
Christian Binggeli, Lukas E Spieker, Roberto Corti, Isabella Sudano, Vesna Stojanovic, Daniel Hayoz, Thomas F Lüscher, Georg Noll, Statins enhance postischemic hyperemia in the skin circulation of hypercholesterolemic patients: a monitoring test of endothelial dysfunction for clinical practice? Journal of the American College of Cardiology. ,vol. 42, pp. 71- 77 ,(2003) , 10.1016/S0735-1097(03)00505-9
Kim M. Gooding, Michael M. Hannemann, John E. Tooke, Geraldine F. Clough, Angela C. Shore, Maximum skin hyperaemia induced by local heating: possible mechanisms. Journal of Vascular Research. ,vol. 43, pp. 270- 277 ,(2006) , 10.1159/000091736
Marco Rossi, Angelo Carpi, Cinzia Di Maria, Fabio Galetta, Gino Santoro, Spectral analysis of laser Doppler skin blood flow oscillations in human essential arterial hypertension Microvascular Research. ,vol. 72, pp. 34- 41 ,(2006) , 10.1016/J.MVR.2006.04.001
Helena Golster, Lars Hyllienmark, Torbjorn Ledin, Johnny Ludvigsson, Folke Sjoberg, Impaired microvascular function related to poor metabolic control in young patients with diabetes. Clinical Physiology and Functional Imaging. ,vol. 25, pp. 100- 105 ,(2005) , 10.1111/J.1475-097X.2004.00596.X
Ana Barac, Umberto Campia, Julio A. Panza, Methods for Evaluating Endothelial Function in Humans Hypertension. ,vol. 49, pp. 748- 760 ,(2007) , 10.1161/01.HYP.0000259601.38807.A6