Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches

作者: Praveen K Sahu , Sanghamitra Satpathi , Prativa K Behera , Saroj K Mishra , Sanjib Mohanty

DOI: 10.3389/FCIMB.2015.00075

关键词:

摘要: Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum infection. It results in high mortality and post-recovery neuro-cognitive disorders children, even after appropriate treatment with effective anti-parasitic drugs. While the complete landscape pathogenesis cerebral still remains to be elucidated, numerous innovative approaches have been developed recent years order improve early detection this neurological syndrome and, subsequently, clinical care affected patients. In review, we briefly summarize current understanding pathogenesis, compile array new biomarkers tools available for diagnosis research, describe emerging therapeutic tackle pathology effectively.

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