Reduction of metformin renal tubular secretion by cimetidine in man.
作者： A Somogyi , C Stockley , J Keal , P Rolan , F Bochner
DOI: 10.1111/J.1365-2125.1987.TB03090.X
关键词:
摘要: … 1 To determine whether cimetidine altered the renal handling of metformin, … cimetidine 0.4 g twice daily. Blood and urine samples were collected and assayed for metformin, cimetidine …
sci-hub.se 参考文章(21)
Malcolm Rowland, Geoffrey Tucker, SYMBOLS IN PHARMACOKINETICS1. British Journal of Clinical Pharmacology. ,vol. 14, pp. 7- 13 ,(1982)
U Lamminsivu, P Karttunen, M Uusitupa, The pharmacokinetics of metformin: a comparison of the properties of a rapid-release and a sustained-release preparation International journal of clinical pharmacology, therapy, and toxicology. ,vol. 21, pp. 31- 36 ,(1983)
GT Tucker, C Casey, PJ Phillips, H Connor, JD Ward, HF Woods, Metformin kinetics in healthy subjects and in patients with diabetes mellitus. British Journal of Clinical Pharmacology. ,vol. 12, pp. 235- 246 ,(1981) , 10.1111/J.1365-2125.1981.TB01206.X
Ellen Burgess, Andrew Blair, Kenneth Krichman, Ralph E. Cutler, Inhibition of Renal Creatinine Secretion by Cimetidine in Humans Kidney & Blood Pressure Research. ,vol. 5, pp. 27- 30 ,(1982) , 10.1159/000172836
P. J. Phillips, R. Scicchitano, A. R. Clarkson, H. R. Gilmore, Metformin Associated Lactic Acidosis Australian and New Zealand Journal of Medicine. ,vol. 8, pp. 281- 284 ,(1978) , 10.1111/J.1445-5994.1978.TB04524.X
Murray R Muirhead, Andrew A Somogyi, Paul E Rolan, Felix Bochner, Effect of cimetidine on renal and hepatic drug elimination: studies with triamterene. Clinical Pharmacology & Therapeutics. ,vol. 40, pp. 400- 407 ,(1986) , 10.1038/CLPT.1986.197
A. Somogyi, A. McLean, B. Heinzow, Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs European Journal of Clinical Pharmacology. ,vol. 25, pp. 339- 345 ,(1983) , 10.1007/BF01037945
Charles D Christian, Christopher G Meredith, K V Speeg, Cimetidine inhibits renal procainamide clearance Clinical Pharmacology & Therapeutics. ,vol. 36, pp. 221- 227 ,(1984) , 10.1038/CLPT.1984.166
Hermann R. Ochs, Roland Gugler, Thomas Guthoff, David J. Greenblatt, Effect of cimetidine on digoxin kinetics and creatinine clearance. American Heart Journal. ,vol. 107, pp. 170- 172 ,(1984) , 10.1016/0002-8703(84)90154-6
Jonas H. Sirota, David S. Baldwin, Herman Villarreal, DIURNAL VARIATIONS OF RENAL FUNCTION IN MAN Journal of Clinical Investigation. ,vol. 29, pp. 187- 192 ,(1950) , 10.1172/JCI102245