Duck immunoglobulins: structure, functions and molecular genetics.
作者： D. A. Higgins , G. W. Warr
DOI: 10.1080/03079459308418916
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摘要: Summary Four types of immunoglobulin (Ig) have been identified in ducks: IgM, a secretory Ig resembling 7.8S IgG, and 5.7S IgG. Structurally antigenically the IgG resembles an F(ab')2 fragment When ducks mount serum antibody responses, sequence involvement is IgM ? Although levels increase, antigen‐binding Igs can be demonstrated, sera from repeatedly immunized commonly lack secondary activities such as agglutination, precipitation, complement fixation tissue sensitization. These deficiencies are most likely attributable to absence functionally important components predominant (5.7S IgG) and/or possibly unusual steric structure duck Igs. A related issue concerns production two IgGs: what cellular molecular events involved, how they controlled? Evidence current genetic studies has confirmed similarity VH, CH1 C...
sci-hub.se 参考文章(97)
J. P. Vaerman, J. Picard, J. F. Heremans, Structural Data on Chicken IgA and Failure to Identify the IgA of the Tortoise Advances in Experimental Medicine and Biology. ,vol. 64, pp. 185- 195 ,(1975) , 10.1007/978-1-4684-3261-9_19
Gregory W. Warr, John J. Marchalonis, Molecular Basis of Self/Non-self Discrimination in the Ectothermic Vertebrates Phylogeny and Ontogeny. pp. 541- 567 ,(1982) , 10.1007/978-1-4684-4166-6_14
R. Parvari, A. Avivi, F. Lentner, E. Ziv, S. Tel-Or, Y. Burstein, I. Schechter, Chicken immunoglobulin gamma-heavy chains: limited VH gene repertoire, combinatorial diversification by D gene segments and evolution of the heavy chain locus. The EMBO Journal. ,vol. 7, pp. 739- 744 ,(1988) , 10.1002/J.1460-2075.1988.TB02870.X
H. Ishiguro, K. Kobayashi, M. Suzuki, K. Titani, S. Tomonaga, Y. Kurosawa, Isolation of a hagfish gene that encodes a complement component. The EMBO Journal. ,vol. 11, pp. 829- 837 ,(1992) , 10.1002/J.1460-2075.1992.TB05120.X
P Porter, S H Parry, Further characterization of IgA in chicken serum and secretions with evidence of a possible analogue of mammalian secretory component. Immunology. ,vol. 31, pp. 407- ,(1976)
A W Payne, L A Gyure, J G Hall, Comparative aspects of the transport of immunoglobulin A from blood to bile. Immunology. ,vol. 41, pp. 899- 902 ,(1980)
Marianne Brüggemann, Chapter 2 Genes encoding the immunoglobulin constant regions New Comprehensive Biochemistry. ,vol. 17, pp. 51- 80 ,(1987) , 10.1016/S0167-7306(08)60154-4
Herman N. Eisen, Edward W. Voss, Anti-Hapten Chicken Antibodies of the 7S Class Journal of Immunology. ,vol. 109, pp. 944- 950 ,(1972)
Howard M. Grey, Duck immunoglobulins. I. Structural studies on a 5.7S and 7.8S gamma-globulin. Journal of Immunology. ,vol. 98, pp. 811- 819 ,(1967)
B. J. Underdown, M. M. Fisher, J. M. Schiff, G. D. F. Jackson, P. J. Barrington, P. G. Walker, A role for the spleen in the appearance of IgM in the bile of rats injected intravenously with horse erythrocytes. Journal of Immunology. ,vol. 135, pp. 152- 157 ,(1985)