Sulfamic Acid: Efficient, Cost-Effective Catalyst for Facile Synthesis of Deazaoxaflavin at Ambient Temperature

作者: Mansing M. Mane , Dattaprasad M. Pore

DOI: 10.1080/00397911.2014.992075

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摘要: AbstractA facile, ecofriendly procedure has been developed for the synthesis of substituted 5-deaza-10-oxaflavins by sulfamic acid–catalyzed two-component condensation salicylaldehyde and barbituric acid at ambient temperature. Mild reaction conditions, short time, temperature, solvent system, wide substrate scope, simple workup procedure, no need chromatographic separation, good yields are auxiliary advantages present protocol.

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