Gliomas: Predicting Time to Progression or Survival with Cerebral Blood Volume Measurements at Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging
作者： Meng Law , Robert J. Young , James S. Babb , Nicole Peccerelli , Sophie Chheang
DOI: 10.1148/RADIOL.2472070898
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摘要: Purpose: To retrospectively determine whether relative cerebral blood volume (CBV) measurements can be used to predict clinical outcome in patients with high-grade gliomas (HGGs) and low-grade (LGGs) specifically who have a high initial CBV more rapid progression than those low CBV. Materials Methods: Approval for this retrospective HIPAA-compliant study was obtained from the Institutional Board of Research Associates, waiver informed consent. One hundred eighty-nine (122 male 67 female patients; median age, 43 years; range, 4–80 years) were examined dynamic susceptibility-weighted contrast material–enhanced perfusion magnetic resonance (MR) imaging followed up clinically MR (median follow-up, 334 days). Log-rank tests evaluate association between time by using Kaplan-Meier curves. Binary logistic regression t...
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