Bacteriophage PRD1: a broad host range DSDNA tectivirus with an internal membrane.

作者: Dennis H. Bamford , Javier Caldentey , Jaana K.H. Bamford

DOI: 10.1016/S0065-3527(08)60064-0

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摘要: Publisher Summary The widely used phage isolation method, described in Adams, includes a chloroform treatment step. As result, bacterial viruses have been considered to be nucleic acid-protein assemblies. omission of the organic solvent from process resulted phages that also had membrane component. Tectiviridae are one most common groups containing biological membrane. divided into two subgroups, those infecting gram-positive and gram-negative hosts. type organism for subgroup is PRD1, other isolates being PR3, PR4, PR5, L17, PR772. best studied members this virus group PRD1 information given review based mostly on results obtained with these systems. A comprehensive description current knowledge related chapter. Two characteristics, particular, drawn attention PRD1-type viruses: (1) virion has an outer rigid protein capsid, inside which resides follows internal capsid surface. (2) viral genome linear dsDNA molecule covalently linked at 5' ends inverted terminal repeat (ITR) sequences both termini.

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