Thirteen novel deoxynivalenol-degrading bacteria are classified within two genera with distinct degradation mechanisms

摘要: The mycotoxin deoxynivalenol (DON), a secondary metabolite produced by species of the plant pathogen Fusarium, causes serious problems in cereal crop production because its toxicity towards humans and livestock. A biological approach for degradation DON using DON-degrading bacterium (DDB) appears to be promising, although information about DDBs is limited. We isolated 13 aerobic from variety environmental samples, including field soils wheat leaves. Of these strains, nine belonged Gram-positive genus Nocardioides other four Gram-negative Devosia. phenotypes two Gram types were clearly different; all washed cells strains degraded 100 μg mL(-1) below detection limit (0.5 mL(-1)), but conditions inducing activities differed between types. HPLC profiles metabolites also distinct genera, 3-epi-deoxynivalenol. showed assimilation media containing as carbon source, whereas Gram-negatives did not. Our results suggest that are distributed within at least phylogenetically restricted suggesting independent evolution DON-degradation mechanisms.