Assay of Sudan I Contamination of Foodstuff by Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry and Isotope Dilution

摘要: Food safety represents one of the main issues national and international agencies appointed to health control. In April 2003, a French agency disclosed that powdered or smashed hot chili pepper imported from India Pakistan was heavily contaminated with carcinogenic azo dye known as Sudan I. This paper deals modern approach for assaying content this colorant in foodstuff down limit few tens parts per billion. The isotope dilution method combined APCI tandem mass spectrometry used. internal standard, 1-(d5-phenylazo)-2-naphthalenol, obtained by simple chemistry, its structure determined 1H NMR spectroscopy. spectrometric is more sensitive than HPLC factor 20.