EGFR and K-ras mutation analysis in non-small cell lung cancer: comparison of paraffin embedded versus frozen specimens.

作者: Giuseppe Giaccone , Katrien Grünberg , Mariëlle I. Gallegos Ruiz , Karijn Floor , José A Rodriguez

DOI: 10.1155/2007/568205

关键词:

摘要: … to obtain a better morphology for immunohistochemistry purposes… In neutral buffered formalin fixed samples, the rate of … have been the result of paraffin embedding and fixation of the …

参考文章(24)
Assessing EGFR mutations. The New England Journal of Medicine. ,vol. 354, pp. 526- ,(2006) , 10.1056/NEJMC052564
Bruce E. Johnson, Pasi A. Jänne, Epidermal Growth Factor Receptor Mutations in Patients with Non–Small Cell Lung Cancer Cancer Research. ,vol. 65, pp. 7525- 7529 ,(2005) , 10.1158/0008-5472.CAN-05-1257
Ming-Sound Tsao, Akira Sakurada, Jean-Claude Cutz, Chang-Qi Zhu, Suzanne Kamel-Reid, Jeremy Squire, Ian Lorimer, Tong Zhang, Ni Liu, Manijeh Daneshmand, Paula Marrano, Gilda da Cunha Santos, Alain Lagarde, Frank Richardson, Lesley Seymour, Marlo Whitehead, Keyue Ding, Joseph Pater, Frances A. Shepherd, Erlotinib in lung cancer - molecular and clinical predictors of outcome. The New England Journal of Medicine. ,vol. 353, pp. 133- 144 ,(2005) , 10.1056/NEJMOA050736
Pasi A. Jänne, Sarada Gurubhagavatula, Beow Y. Yeap, Joan Lucca, Patricia Ostler, Arthur T. Skarin, Panos Fidias, Thomas J. Lynch, Bruce E. Johnson, Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839, ‘Iressa’) on an expanded access study Lung Cancer. ,vol. 44, pp. 221- 230 ,(2004) , 10.1016/J.LUNGCAN.2003.12.014
William Pao, Vincent A Miller, Katerina A Politi, Gregory J Riely, Romel Somwar, Maureen F Zakowski, Mark G Kris, Harold Varmus, Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain PLoS Medicine. ,vol. 2, pp. e73- ,(2005) , 10.1371/JOURNAL.PMED.0020073
YR Chen, YN Fu, CH Lin, ST Yang, SF Hu, YT Chen, SF Tsai, SF Huang, None, Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants Oncogene. ,vol. 25, pp. 1205- 1215 ,(2006) , 10.1038/SJ.ONC.1209159
Giuseppe Giaccone, Epidermal Growth Factor Receptor Inhibitors in the Treatment of Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 23, pp. 3235- 3242 ,(2005) , 10.1200/JCO.2005.08.409
Teruhiko Inoue, Kazuki Nabeshima, Hiroaki Kataoka, Masashi Koono, Feasibility of archival non-buffered formalin-fixed and paraffin-embedded tissues for PCR amplification: an analysis of resected gastric carcinoma. Pathology International. ,vol. 46, pp. 997- 1004 ,(1996) , 10.1111/J.1440-1827.1996.TB03580.X
Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, Sarada Gurubhagavatula, Ross A. Okimoto, Brian W. Brannigan, Patricia L. Harris, Sara M. Haserlat, Jeffrey G. Supko, Frank G. Haluska, David N. Louis, David C. Christiani, Jeff Settleman, Daniel A. Haber, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib The New England Journal of Medicine. ,vol. 350, pp. 2129- 2139 ,(2004) , 10.1056/NEJMOA040938