作者: Andrew R. Harwood , J. Ivan Krajbich , Victor L. Fornasier
DOI: 10.1002/1097-0142(19800601)45:11<2769::AID-CNCR2820451111>3.0.CO;2-X
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摘要: A retrospective analysis of 31 cases chondrosarcoma bone treated by radiotherapy is presented. In comparison with other large series, our group patients were found to have been unfavourably selected respect the known prognostic factors: histology site, adequacy operative treatment, and presenting symptoms. Twelve primary radically irradiated; 6 these 12 alive well without tumor for periods ranging from three a half 16 years 3 are 15 or more following radiotherapy. The responded desease stabilized months eight years. One poorly differentiated was irradiated did not respond. Eleven palliatively, generally low doses irradiation, only 4 transiently months. Seven mesenchymal dedifferentiated tumors irradiated. Four disease stabilized, 1 at years; Six died distant metastasis. It concluded that radioresponsive place inmore » treatment this reason its being labelled radioresistant discussed. problems assessing response therapy also suggested chemotherapy may role in management chondrosarcoma.« less