Initial prevalence of anal human papilloma virus infection in liver transplant recipients.

摘要: Summary Although liver transplant recipients are at increased risk of human papilloma virus (HPV)-related anal cancer, limited data available regarding the initial prevalence HPV infection in this population. Anal swabs collected from 50 within first three postoperative weeks were subjected to real-time polymerase chain reaction for detection four genotypes: 6, 11, 16, and 18. Predictors any, low-risk, high-risk evaluated. Overall, any was 18.0%, with corresponding rates high- low-risk genotypes being 8.0% 10.0%, respectively. Infection type higher patients hepatitis B (HBV) (P = 0.027), ≥3 sexual partners (P = 0.031), alcoholic disease (P = 0.063). HBV only factor significantly associated (P = 0.038). Male sex (P = 0.050), age ≥52 years (P = 0.016), ≥30 (P = 0.003), intercourse ≤18 years (P = 0.045), time since ≥38 years (P = 0.012) identified as predictors infection. These results indicate that vaccination candidates screening groups should be considered.