Synthesis, Characterization, and In Vitro Studies of an Reactive Oxygen Species (ROS)-Responsive Methoxy Polyethylene Glycol-Thioketal- Melphalan Prodrug for Glioblastoma Treatment
作者： Natalia Oddone , Frank Boury , Emmanuel Garcion , Andreas M. Grabrucker , M. Carmen Martinez
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摘要: … (proline), phenyl boronic ester, and more recently thioketal (TK) were used as … mPEG-TK-COOH polymer, to produce a ROS-responsive antitumor prodrug with MPH, namely mPEG-TK-…
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