Targeting miR-21 in glioma: a small RNA with big potential.
作者： Lynette M Moore , Wei Zhang
DOI: 10.1517/14728222.2010.527334
关键词:
摘要: Importance of the field: Glioma therapies have produced relatively small improvements over past decade, highlighting an important need to identify novel ways target this disease. Targeted against single activated protein kinases proven effective in some cancers including gastrointestinal stromal cancer and colon cancer, but not yet gliomas where multiple pathways targets may be involved. MicroRNAs are emerging as key regulators involved development progression become next targeted glioma. Areas covered review: This review covers basics microRNA biology specifically focuses on roles miR-21 glioma its potential for therapy. What reader will gain: provide with depth understanding how functions We also current state studies designed a future therapeutic. Take...
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