Cyclodextrins in non-viral gene delivery.

作者: Wing-Fu Lai

DOI: 10.1016/J.BIOMATERIALS.2013.09.061

关键词:

摘要: Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides. They consist of (α-1, 4)-linked glucose units, and possess a basket-shaped topology with an “inner–outer” amphiphilic character. Over the years, substantial efforts have been undertaken to investigate the possible use of CDs in drug delivery and controlled drug release, yet the potential of CDs in gene delivery has received comparatively less discussion in the literature. In this article, we will first discuss the properties of CDs for gene delivery, followed …

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