Factors predicting recurrence after curative resection for rectal cancer: a 16-year study.
作者： Mohamed Kahloul , Rahul Gupta , Mohamed Ben Mabrouk , Ali Ben Ali
DOI: 10.1186/S12957-019-1718-1
关键词:
摘要: The recurrence after curative surgery of the rectal adenocarcinoma is a serious complication, considered as failure therapeutic strategy. aim this study was to identify different prognostic factors affecting rectum. A retrospective analysis patients operated for rectum between January 2000 and December 2015 conducted. rate performed through Kaplan Meier survival curve Cox regression analysis. During period, 188 underwent adenocarcinoma, among which 53 had recurrence. 44.6% at 5 years. multivariate identified four parameters independently associated with risk surgery: distal margin ≤ 2 cm (HR = 6.8, 95% CI 2.7–16.6, 6), extracapsular invasion lymph node metastasis (HR = 4.4, 1.3–14), tumor stenosis (HR = 4.3, 1.2–15.2), parietal (pT3/T4 disease) (HR = 3, 1.1–9.4). determination allows us define high-risk ClinicalTrials.gov Identifier: NCT03899870 . Registered on 2 February 2019, retrospectively registered.
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