PIK3CA in breast carcinoma: a mutational analysis of sporadic and hereditary cases.

作者: Angela Michelucci , Claudio Di Cristofano , Azzurra Lami , Paola Collecchi , Adelaide Caligo

DOI: 10.1097/PDM.0B013E31818E5FA4

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摘要: The PI3K-Akt cascade is a key signaling pathway involved in cell proliferation, survival, and growth. Activating PIK3CA mutations have been reported breast carcinoma (BC). aim of this study was to characterize the at exons 9 20 series 176 sporadic 22 hereditar

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