Distinct Somatic Genetic Changes Associated with Tumor Progression in Carriers of BRCA1 and BRCA2 Germ-line Mutations

作者: Ritva Karhu , Rosa B. Barkardottir , Bjarni A. Agnarsson , Jorma Isola , Oskar Johannsson

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摘要: BRCA1 and BRCA2 mutations confer increased risk for development of breast cancer, but a number of additional, currently largely unknown, somatic genetic defects must also …

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