Length Analysis of Polymerase Chain Reaction Products: A Sensitive and Reliable Technique for the Detection of Mutations in KIT Exon 11 in Gastrointestinal Stromal Tumors

作者: Jean-François Emile , Antoinette Lemoine , Nathalie Bienfait , Philippe Terrier , Daniel Azoulay

DOI: 10.1097/00019606-200206000-00007

关键词:

摘要: Gastrointestinal stromal tumors are the most common mesenchymal neoplasms of digestive tract. These express c-kit receptor tyrosine kinase, and many have activating mutations in juxtamembrane region coded by exon 11 KIT. Detection these has prognostic thera

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