Species differentiation and quality assessment of Radix Paeoniae Rubra (Chi-shao) by means of high-performance liquid chromatographic fingerprint

摘要: There are two species under the monograph of Radix Paeoniae Rubrae ("Chi-shao" in Chinese) Chinese Pharmacopoeia 2005 edition-Paeonia lactiflora Pallas and Paeonia veitchii Lynch. Due to different growing conditions, there significant chemical differences between species, which may result improper clinical usage same name. Chemical pattern expressed by high performance liquid chromatographic (HPLC) fingerprint analysis can play an important role differentiation quality control Rubra. In present work, HPLC fingerprints kinds Rubra have been established analysed with chemometric methods including similarity evaluation principal component analysis. Both common patterns comprise 13 characteristic peaks, nine were peaks species. However, roots P. exist not only content certain constituents, especially phenolic acids but also peak-to-peak ratios patterns. According recent pharmacological studies on polyphenolic root originating from possess better efficacy than that lactiflora. Our research reveals further investigation is very necessary determine whether should be embodied Pharmacopoeia.