TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

作者: Ting Li , Sheng Huang , Wen Zhi Jiang , David Wright , Martin H. Spalding

DOI: 10.1093/NAR/GKQ704

关键词:

摘要: DNA double-strand breaks enhance homologous recombination in cells and have been exploited for targeted genome editing through use of engineered endonucleases. Here we …

参考文章(49)
J Keith Joung, Daniel F Voytas, Toni Cathomen, Reply to “Genome editing with modularly assembled zinc-finger nucleases” Nature Methods. ,vol. 7, pp. 91- 92 ,(2010) , 10.1038/NMETH0210-91B
Doreen Gürlebeck, Boris Szurek, Ulla Bonas, Dimerization of the bacterial effector protein AvrBs3 in the plant cell cytoplasm prior to nuclear import Plant Journal. ,vol. 42, pp. 175- 187 ,(2005) , 10.1111/J.1365-313X.2005.02370.X
J Fishman-Lobell, N Rudin, J E Haber, Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Molecular and Cellular Biology. ,vol. 12, pp. 1292- 1303 ,(1992) , 10.1128/MCB.12.3.1292
Toni Cathomen, J Keith Joung, Zinc-finger Nucleases: The Next Generation Emerges Molecular Therapy. ,vol. 16, pp. 1200- 1207 ,(2008) , 10.1038/MT.2008.114
FRANK F. WHITE, NEHA POTNIS, JEFFREY B. JONES, RALF KOEBNIK, The type III effectors of Xanthomonas Molecular Plant Pathology. ,vol. 10, pp. 749- 766 ,(2009) , 10.1111/J.1364-3703.2009.00590.X
Yuka Shimizu, Mital S. Bhakta, David J. Segal, Restricted spacer tolerance of a zinc finger nuclease with a six amino acid linker Bioorganic & Medicinal Chemistry Letters. ,vol. 19, pp. 3970- 3972 ,(2009) , 10.1016/J.BMCL.2009.02.109
Éva Scheuring Vanamee, Sandro Santagata, Aneel K Aggarwal, FokI requires two specific DNA sites for cleavage. Journal of Molecular Biology. ,vol. 309, pp. 69- 78 ,(2001) , 10.1006/JMBI.2001.4635
J. Boch, H. Scholze, S. Schornack, A. Landgraf, S. Hahn, S. Kay, T. Lahaye, A. Nickstadt, U. Bonas, Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors Science. ,vol. 326, pp. 1509- 1512 ,(2009) , 10.1126/SCIENCE.1178811
A. Sugio, B. Yang, T. Zhu, F. F. White, Two type III effector genes of Xanthomonas oryzae pv. oryzae control the induction of the host genes OsTFIIAγ1 and OsTFX1 during bacterial blight of rice Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 10720- 10725 ,(2007) , 10.1073/PNAS.0701742104