Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models.

作者: Hongbin Ji , Zhenxiong Wang , Samanthi A. Perera , Danan Li , Mei-Chih Liang

DOI: 10.1158/0008-5472.CAN-06-4592

关键词:

摘要: Mutations in the BRAF and KRAS genes occur in ∼1% to 2% and 20% to 30% of non–small-cell lung cancer patients, respectively, suggesting that the mitogen-activated protein kinase (…

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