Modeling Human Colorectal Cancer in Mice for Chemoprevention Studies

作者: Martin Lipkin , Sergio A. Lamprecht

DOI: 10.1007/978-1-59259-768-0_4

关键词:

摘要: New approaches to chemoprevention studies have evolved from a better understanding of the genetics and molecular biology cancer. Previous research has focused on human cancer cell lines xenografts cells in immunologically compromised mice. Though these experimental provided much information cells, they precluded any insight into intricate cross-talk between transformed host vivo (1,2).

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