Joshua A. Lerman
机构: Director of Computation, Bota Biosciences
每年引用次数
引用次数
引用: 6,302
H-指数: 15
I10-指数 : 16
出版物: 24
Genome-scale Models of Metabolism and Gene Expression: Construction and Use for Growth Phenotype Prediction
Joshua Adam Lerman
UC San Diego
2014
Reconstruction and modeling protein translocation and compartmentalization in Escherichia coli at the genome-scale
Joanne K Liu , Edward J O’Brien , Joshua A Lerman , Karsten Zengler
BMC Systems Biology 8 ( 1) 110 -110
68
2014
An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92.
Pep Charusanti , Sadhana Chauhan , Kathleen McAteer , Joshua A Lerman
BMC Systems Biology 5 ( 1) 163 -163
30
2011
COBRApy: COnstraints-Based Reconstruction and Analysis for Python.
Ali Ebrahim , Joshua A Lerman , Bernhard O Palsson , Daniel R Hyduke
BMC Systems Biology 7 ( 1) 74 -74
907
2013
Omic data from evolved E. coli are consistent with computed optimal growth from genome‐scale models
Nathan E Lewis , Kim K Hixson , Tom M Conrad , Joshua A Lerman
Molecular Systems Biology 6 ( 1) 390 -390
657
2010
A comprehensive genome‐scale reconstruction of Escherichia coli metabolism—2011
Jeffrey D Orth , Tom M Conrad , Jessica Na , Joshua A Lerman
Molecular Systems Biology 7 ( 1) 535 -535
1,173
2011
Genome‐scale models of metabolism and gene expression extend and refine growth phenotype prediction
Edward J O'Brien , Joshua A Lerman , Roger L Chang , Daniel R Hyduke
Molecular Systems Biology 9 ( 1) 693 -693
317
2013
Do Genome-scale Models Need Exact Solvers or Clearer Standards?
Ali Ebrahim , Eivind Almaas , Eugen Bauer , Aarash Bordbar
Molecular Systems Biology 11 ( 10) 831 -831
64
2015
An automated scientist to design and optimize microbial strains for the industrial production of small molecules
Amoolya H Singh , Benjamin B Kaufmann-Malaga , Joshua A Lerman , Daniel P Dougherty
bioRxiv 2023.01. 03.521657 -2023.01. 03.521657
5
2023
Method for in silico Modeling of Gene Product Expression and Metabolism
Daniel R Hyduke , Joshua A Lerman , Bernhard O Palsson , Edward O'brien
2015
Biosynthesis of compounds in yeast
Michael Leavell , Joshua A. Lerman , Jessica Walter , Benjamin Yap
2019
Reconciling a Salmonella enterica metabolic model with experimental data confirms that overexpression of the glyoxylate shunt can rescue a lethal ppc deletion mutant.
Nicole L. Fong , Joshua A. Lerman , Irene Lam , Bernhard O. Palsson
Fems Microbiology Letters 342 ( 1) 62 -69
7
2013
Raloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulence.
Shannan J. Ho Sui , Raymond Lo , Aalton R. Fernandes , Mackenzie D.G. Caulfield
International Journal of Antimicrobial Agents 40 ( 3) 246 -251
60
2012
The Genome Organization of Thermotoga maritima Reflects Its Lifestyle
Haythem Latif , Joshua A. Lerman , Vasiliy A. Portnoy , Yekaterina Tarasova
PLoS Genetics 9 ( 4) e1003485
37
2013
Multi-omic data integration enables discovery of hidden biological regularities
Ali Ebrahim , Elizabeth Brunk , Justin Tan , Edward J. O'Brien
Nature Communications 7 ( 1) 13091
109
2016
In silico method for modelling metabolism and gene product expression at genome scale
Joshua A. Lerman , Daniel R. Hyduke , Haythem Latif , Vasiliy A. Portnoy
Nature Communications 3 ( 1) 929 -929
310
2012
BiGG Models: A platform for integrating, standardizing and sharing genome-scale models
Zachary A. King , Justin S. Lu , Andreas Dräger , Philip C. Miller
Nucleic Acids Research
908
2015
Determining the control circuitry of redox metabolism at the genome-scale.
Stephen Federowicz , Donghyuk Kim , Ali Ebrahim , Joshua Lerman
PLOS Genetics 10 ( 4)
45
2014
Multifunctional neck brace
Peter Gehlbach , Brian Benson , Helena Cortes , Michael Davenport
6
2008
Methods for decoupling yield and productivity of a non-catabolic compound produced by a host cell
Penelope Chua , Joshua Lerman , Thomas Scherbart , Chandresh Thakker
2022