Yusaku Nakabeppu
机构: Division of Neurofunctional Genomics, Medical Institute of Bioregulation, Kyushu University
主页: kyushu-u.ac.jp
每年引用次数
引用次数
引用: 25,012
H-指数: 83
I10-指数 : 259
出版物: 317
Oxidative stress induces different tissue dependent effects on Mutyh-deficient mice.
Jingwen Chen , Zhenqian Huang , Xin Wu , Jiaqi Kang
Free Radical Biology and Medicine 143 482 -493
4
2019
NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest
Teruaki Iyama , Nona Abolhassani , Daisuke Tsuchimoto , Mari Nonaka
Nucleic Acids Research 38 ( 14) 4834 -4843
38
2010
Genomic Structure and Chromosome Location of the Human mutT Homologue Gene MTH1 Encoding 8-Oxo-dGTPase for Prevention of A:T to C:G Transversion
Masato Furuichi , Michihiro C. Yoshida , Hisanobu Oda , Tatsurou Tajiri
Genomics 24 ( 3) 485 -490
126
1994
DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1
Sarah A. Martin , Nuala McCabe , Michelle Mullarkey , Robert Cummins
Cancer Cell 17 ( 3) 235 -248
150
2010
The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice.
Hisanao Izumi , Yasuharu Shinoda , Takashi Saito , Takaomi C. Saido
Neuroscience 377 87 -97
15
2018
Some flavonoids and DHEA-S prevent the cis-effect of expanded CTG repeats in a stable PC12 cell transformant.
Hirokazu Furuya , Nobue Shinnoh , Yasumasa Ohyagi , Koji Ikezoe
Biochemical Pharmacology 69 ( 3) 503 -516
16
2005
Therapeutic effects of hydrogen in animal models of Parkinson's disease.
Kyota Fujita , Yusaku Nakabeppu , Mami Noda
Parkinson's Disease 2011 307875 -307875
16
2011
Narrow-Band UVB Induces More Carcinogenic Skin Tumors than Broad-Band UVB through the Formation of Cyclobutane Pyrimidine Dimer
Makoto Kunisada , Hiroshi Kumimoto , Kanji Ishizaki , Kunihiko Sakumi
Journal of Investigative Dermatology 127 ( 12) 2865 -2871
97
2007
Regulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription products.
Hisanobu Oda , Yusaku Nakabeppu , Masato Furuichi , Mutsuo Sekiguchi
Journal of Biological Chemistry 272 ( 28) 17843 -17850
57
1997
XRCC1 interactions with multiple DNA glycosylases: A model for its recruitment to base excision repair
Anna Campalans , Stéphanie Marsin , Yusaku Nakabeppu , Timothy R. O’Connor
DNA Repair 4 ( 7) 826 -835
146
2005
MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.
Yusaku Nakabeppu , Kosuke Kajitani , Katsumi Sakamoto , Hiroo Yamaguchi
DNA Repair 5 ( 7) 761 -772
67
2006
RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.
Isao Kuraoka , Kyoko Suzuki , Shinsuke Ito , Mika Hayashida
DNA Repair 6 ( 6) 841 -851
64
2007
Accumulation of 8-oxo-deoxyguanosine in cardiovascular tissues with the development of hypertension.
Toshio Ohtsubo , Yusuke Ohya , Yoshito Nakamura , Yasuo Kansui
DNA Repair 6 ( 6) 760 -769
21
2007
Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death.
Junji Ichikawa , Daisuke Tsuchimoto , Sugako Oka , Mizuki Ohno
DNA Repair 7 ( 3) 418 -430
44
2008
Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus.
Yukihiko Dan , Yutaka Ohta , Daisuke Tsuchimoto , Mizuki Ohno
DNA Repair 7 ( 9) 1437 -1454
7
2008
Impaired spermatogenesis and elevated spontaneous tumorigenesis in xeroderma pigmentosum group A gene (Xpa)-deficient mice.
Hironobu Nakane , Seiichi Hirota , Philip J. Brooks , Yusaku Nakabeppu
DNA Repair 7 ( 12) 1938 -1950
19
2008
Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study
Masaaki Hokama , Sugako Oka , Julio Leon , Toshiharu Ninomiya
Cerebral Cortex 24 ( 9) 2476 -2488
297
2014
A Role for SNX1 in the Regulation of EGF-Dependent Phosphorylated EGFR Endocytosis Via the Early/Late Endocytic Pathway in a Gefitinib-Sensitive Human Lung Cancer Cells
Yukio Nishimura , Kiyoko Yoshioka , Soichi Takiguchi , Biborka Bereczky
Current Signal Transduction Therapy 6 ( 3) 383 -395
6
2011
Skin tumours induced by narrowband UVB have higher frequency of p53 mutations than tumours induced by broadband UVB independent of Ogg1 genotype
Flandiana Yogianti , Makoto Kunisada , Ryusuke Ono , Kunihiko Sakumi
Mutagenesis 27 ( 6) 637 -643
18
2012
Cellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cells.
Yusaku Nakabeppu
International Journal of Molecular Sciences 15 ( 7) 12543 -12557
206
2014
Eric Nestler JULIO LEON Tomofumi Miura George S Robertson Chikako Nishigori Frank LaFerla Mehrdad Behmanesh takaomi saido Masayuki TAKAHASHI Paul Worley Takashi Saito Shinya Toyokuni Flandiana Yogianti Ryusuke Ono Andrew J. Cole Erika Castillo Harini Sampath Robert J. Christy Michael J Iadarola Victor Thijssen