Repeated treatment with antidepressant drugs increases the behavioural response to apomorphine.
作者： J. Maj , Z. Rogóż , G. Skuza , H. Sowińska
DOI: 10.1007/BF01249099
关键词: Amitriptyline 、 Zimelidine 、 Open field 、 Antidepressant 、 Psychology 、 Pharmacology 、 Imipramine 、 Citalopram 、 Mianserin 、 Apomorphine
摘要: The effect of repeated treatment (twice a day for 14 days) with antidepressant drugs (AD): imipramine, amitriptyline, zimelidine, citalopram and mianserin on the behavioural response to apomorphine in rats (open field test) was investigated. AD studied, given alone single dose or repeatedly, do not change behaviour. A but single-dose facilitates behaviour stimulation induced by apomorphine. This facilitation is observed 2 hours after last 72 amitriptyline.
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