Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro

作者: Guoqiang Jiang , Jia Liu , Baoyin Ren , Lin Zhang , Lawrence Owusu

DOI: 10.1016/J.JEP.2017.04.026

关键词: ChemistryApoptosisViability assayCancer cellOvarian cancerCisplatinMTT assaySalvia miltiorrhizaMetastasisPharmacology

摘要: … In this study, we evaluated the inhibitory effect of Cryptotanshinone on ovarian cancer cells … Cryptotanshinone inhibited the growth of ovarian cancer cells. In addition, Cryptotanshinone …

参考文章(37)
Brucks Ja, Ovarian cancer. The most lethal gynecologic malignancy. Nursing Clinics of North America. ,vol. 27, pp. 835- 845 ,(1992)
Sudhakar V. Nuti, Gil Mor, Peiyao Li, Gang Yin, TWIST and ovarian cancer stem cells: implications for chemoresistance and metastasis Oncotarget. ,vol. 5, pp. 7260- 7271 ,(2014) , 10.18632/ONCOTARGET.2428
Benoît Thibault, Magali Castells, Jean-Pierre Delord, Bettina Couderc, Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition Cancer and Metastasis Reviews. ,vol. 33, pp. 17- 39 ,(2014) , 10.1007/S10555-013-9456-2
T. Grzela, J. Niderla-Bielinska, M. Litwiniuk, R. White, The Direct Inhibition of MMP–2 and MMP–9 by an Enzyme Alginogel: A Possible Mechanism of Healing Support for Venous Leg Ulcers Journal of Wound Care. ,vol. 23, pp. 278- 285 ,(2014) , 10.12968/JOWC.2014.23.5.278
In-Ja Park, Min-Jung Kim, Ock Jin Park, Wonchae Choe, Insug Kang, Sung-Soo Kim, Joohun Ha, Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells Apoptosis. ,vol. 17, pp. 248- 257 ,(2012) , 10.1007/S10495-011-0680-3
Weilan Wang, Kaixu Chen, Qing Liu, Nathan Johnston, Zhenghai Ma, Fuchun Zhang, Xiufen Zheng, Suppression of Tumor Growth by Pleurotus ferulae Ethanol Extract through Induction of Cell Apoptosis, and Inhibition of Cell Proliferation and Migration PLoS ONE. ,vol. 9, pp. e102673- ,(2014) , 10.1371/JOURNAL.PONE.0102673
LIANG CHEN, HUI-JUAN WANG, WENLI XIE, YUNYI YAO, YAN-SHAN ZHANG, HUILING WANG, Cryptotanshinone inhibits lung tumorigenesis and induces apoptosis in cancer cells in vitro and in vivo. Molecular Medicine Reports. ,vol. 9, pp. 2447- 2452 ,(2014) , 10.3892/MMR.2014.2093
Yan Fang Zhang, Min Zhang, Xu Lei Huang, Yu Jie Fu, Yu Han Jiang, Ling Ling Bao, Yasen Maimaitiyiming, Guang Ji Zhang, Qian Qian Wang, Hua Naranmandura, The combination of arsenic and cryptotanshinone induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in breast cancer cells Metallomics. ,vol. 7, pp. 165- 173 ,(2015) , 10.1039/C4MT00263F