Gender and post-ischemic recovery of hypertrophied rat hearts.
作者： Ramesh Saeedi , Richard B Wambolt , Hannah Parsons , Christine Antler , Hon S Leong
关键词: Metabolism 、 Oxidation reduction 、 Sex factors 、 Medicine 、 Angiology 、 Endocrinology 、 Cardiac response 、 Myocardial ischemia 、 Internal medicine 、 Glycolysis 、 Lactate oxidation
摘要: Background Gender influences the cardiac response to prolonged increases in workload, with differences at structural, functional, and molecular levels. However, it is unknown if post-ischemic function or metabolism of female hypertrophied hearts differ from male hearts. Thus, we tested hypothesis that gender pressure-overload determined effect on outcome could be explained by metabolism, especially catabolic fate glucose.
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