作者: F Castell , G J R Cook
关键词: Oncology 、 Medical physics 、 Treatment response 、 Kinetic analysis 、 Clinical trial 、 Positron emission tomography 、 18fdg pet 、 Internal medicine 、 Medicine
摘要: The clinical applications of 18F-fluoro-2-deoxyglucose (18FDG) positron emission tomography (PET) in oncology are becoming established. While simple static scanning techniques used for the majority routine examinations, increasing use PET trials to monitor treatment response with 18FDG and novel tracers reflecting different pharmacodynamic end points, often necessitates a more complex quantitative analysis radiopharmaceutical kinetics. A wide range exist, ranging from visual semiquantitative methods full dynamic studies kinetic analysis. These discussed, focusing particularly on available methodologies that can be utilised trials.