Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer
作者： Anna H. Larsson , Sophie Lehn , Sakarias Wangefjord , Emelie Karnevi , Eugenia Kuteeva
DOI: 10.1186/S12967-016-0882-0
关键词: Gene 、 Mutation 、 Immunohistochemistry 、 Chromosome 7 (human) 、 In vivo 、 Cancer research 、 Epidermal growth factor receptor 、 Colorectal cancer 、 Transmembrane protein 、 Medicine
摘要: Background Podocalyxin-like 1 (PODXL) is an anti-adhesive transmembrane protein that has been demonstrated to be independent factor of poor prognosis in colorectal cancer (CRC). The gene encoding PODXL located chromosome 7, which also harbours the for epidermal growth receptor (EGFR). aim this study was examine associations between and EGFR expression CRC vitro vivo.
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