Radiotherapy in the treatment of low-grade astrocytomas. II. The physical and cognitive sequelae.

作者: Richard D. Chadderton , Charles G. H. West , Stephan Schulz , D. Christopher Quirke , Rao Gattamaneni

DOI: 10.1007/BF00334961

关键词: Combined Modality TherapyNeurosurgeryRadiologyCentral nervous system diseaseCognitionMedicineIncidence (epidemiology)Radiation therapySequelaEl NiñoSurgery

摘要: The purpose of the present study was to define late effects, both physical and psychological, treating low-grade astrocytomas with radiotherapy. Fifty patients, half whom received radiotherapy, underwent an assessment neurological neuropsychological function. There no difference in function between two groups. radiotherapy recipients, including those cerebellar tumours, performed significantly worse on measures intelligence information processing. In addition, there a greater incidence special education needs irradiated group. We conclude that children who receive have deficit but use carries penalty terms long-term cognitive confirmed findings many previous reports supratentorial irradiation is detrimental. More surprisingly, it has been demonstrated local field posterior fossa can also produce significant impairment.

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