Regurgitant fraction measured by using the proximal isovelocity surface area method in dogs with chronic myxomatous mitral valve disease.

摘要: Previous studies have demonstrated that regurgitant fraction can be measured by using the proximal isovelocity surface area (PISA) method. For this study, we utilized Doppler echocardiographic method to estimate magnitude of mitral regurgitation in dogs with myxomatous valve disease. Seventeen older, small chronic and no mild myocardial failure were studied. A blinded observer judged clinical severity mild, moderate, or severe assessment left heart size. The was calculated PISA spectral echocardiography. compared for each dog calculations atrial Five had clinically regurgitation. Four these a between 22 41%, whereas 1 73%. 3 evidence moderate 46-65%. All 9 greater than 75% (78-88%). statistically different group (P 75%), disease lesser degrees Good correlation found We conclude major determinant size mitrial is degree