STUDIES OF NATURAL POPULATIONS OF MUS. II. POLYMORPHISM AT THE T LOCUS.

作者: Michael L. Petras

DOI: 10.1111/J.1558-5646.1967.TB03403.X

关键词: Locus (genetics)SpermGeneticsAlleleTransmission ratioSterilityBiologyHouse mouse

摘要: Studies of a number natural populations the house mouse, Mus musculus, by Dunn and his collaborators (Dunn Morgan, 1953; Dunn, 1955; Suckling, 1956; Beasley, Tinker, 1960; Anderson, 1964) have revealed existence widespread polymorphism at T locus. This consists series alleles which are concerned with development axial structures in caudal region mouse. These alleles, t-alleles, divided into two major groups depending on their effect homozygous condition. Some when present condition (t/t) result prenatal mortality described as lethals. Other t-alleles cause only male sterility, all homozygotes being viable. In view selective disadvantage ubiquity is unexpected. The force keeping these an abnormal transmission ratio favors t-bearing sperm heterozygous (+/t) males (Dunn, 1957). Since locus examination was included this study to support conclusions about breeding structure reached from data other loci (Petras, 1965, 1967). process, information obtained about: (1) frequency wild populations, (2) fluctua-

参考文章(10)
L. C. Dunn, Andrew B. Beasley, Harriet Tinker, Polymorphisms in Populations of Wild House Mice Journal of Mammalogy. ,vol. 41, pp. 220- 229 ,(1960) , 10.2307/1376356
D. Bruck, MALE SEGREGATION RATIO ADVANTAGE AS A FACTOR IN MAINTAINING LETHAL ALLELES IN WILD POPULATIONS OF HOUSE MICE. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 43, pp. 152- 158 ,(1957) , 10.1073/PNAS.43.1.152
L. C. Dunn, W. C. Morgan, Alleles at a Mutable Locus Found in Populations of Wild House Mice (Mus Musculus). Proceedings of the National Academy of Sciences of the United States of America. ,vol. 39, pp. 391- 402 ,(1953) , 10.1073/PNAS.39.5.391
L. C. Dunn, Variations in the Transmission Ratios of Alleles Through Egg and Sperm in Mus musculus The American Naturalist. ,vol. 94, pp. 385- 393 ,(1960) , 10.1086/282142
L. C. Dunn, EVIDENCE OF EVOLUTIONARY FORCES LEADING TO THE SPREAD OF LETHAL GENES IN WILD POPULATIONS OF HOUSE MICE. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 43, pp. 158- 163 ,(1957) , 10.1073/PNAS.43.1.158
R. C. Lewontin, L. C. Dunn, The Evolutionary Dynamics of a Polymorphism in the House Mouse. Genetics. ,vol. 45, pp. 705- 722 ,(1960) , 10.1093/GENETICS/45.6.705