Cells in the marginal zone of the spleen.

作者: Georg Kraal

DOI: 10.1016/S0074-7696(08)62453-5

关键词: Cell biologyBiologyLymphatic systemB cellRed pulpAnatomyReticular cellSpleenWhite pulpCompartment (pharmacokinetics)Marginal zone

摘要: Publisher Summary This chapter provides an overview of the various nonlymphoid and lymphoid cell types localized in marginal zone way they are arranged basic structure this compartment. It also discusses role zone, with emphasis to intriguing ways these interact each other defense against invading pathogens. The spleen can be divided into a red pulp compartment, distinguishable by abundance erythrocytes, white consisting large nodules organized tissue. is that blood filtration takes place, whereas involved specific immunological bloodborne antigens. described as layer surrounding periarteriolar lymphocyte sheath (PALS) B follicles, predominantly composed intermediate-sized lymphocytes. consists meshwork reticular cells, which concentrically layered around PALS follicular areas, more dispersed three-dimensional appearance toward pulp. opening part arterial supply wider spaces sinus, right at border pulp, results flow lower resistance.

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