Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity
作者： Himisha Beltran , Roman Yelensky , Garrett M. Frampton , Kyung Park , Sean R. Downing
DOI: 10.1016/J.EURURO.2012.08.053
关键词: Mutation 、 Deep sequencing 、 PTEN 、 Regulation of gene expression 、 TMPRSS2 、 Oncogene 、 Gene 、 Cancer 、 Medicine 、 Cancer research 、 Urology
摘要: … targeted sequencing using advanced prostate tumor FFPE samples. We show that this targeted … value of comprehensive genomic profiling for targeted therapy selection in clinical care. …
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